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Behçet's disease - syndrome

Disease
Behçet's disease is a chronic multisystem inflammatory syndrome that may include anterior uveitis, posterior uveitis and retinal vasculitis. The disease has a characteristic diagnostic triad of iritis, oral and genital ulcers.

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SYMPTOMS

If uveitis is present in Behçet's disease, then ocular symptoms may include blurring of vision, photophobia and ocular pain, usually bilaterally.

SIGNS

In mild cases of Behçet's disease, the oral or genital ulcers, or other skin lesions, may be the only findings; however, occasionally ocular disease may be the initial finding. When present, the uveitis may be severe and recurrent, with hypopyon, iridocyclitis, posterior synechiae, papilloedema, vitritis and cystoid macula oedema. An occlusive vasculitis may also occur, with retinal haemorrhages, oedema and vascular sheathing.

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