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Non-proliferative diabetic retinopathy (NPDR) consists of a range of clinical signs that confirm the onset of diabetes-associated retinal damage.

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Non-proliferative diabetic retinopathy (NPDR) consists of a range of clinical signs that confirm the onset of diabetes-associated retinal damage.

Although most patients with NPDR do not require specific ocular treatment, regular review is required to allow prompt detection and/or treatment of proliferative diabetic retinopathy (PDR), thought to result from retinal ischaemia, or diabetic macular oedema (DME), related to leaking retinal vessels.

Symptoms

NPDR is usually asymptomatic.

Signs

The International Clinical Diabetic Retinopathy Disease Severity Scale grades NPDR as follows (see Diabetes - introduction to retinopathy, for explanation of terms):

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