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Diagnosis and management of multiple white lesions at the posterior pole

Disease
Christina A Rennie, Sam Khandhadia and Richard Newsom conclude their two-part feature on white dot syndromes with the differential diagnosis of inflammatory and miscellaneous lesions

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The white-dot syndromes are a distinctive group of disorders producing yellow-white inflammatory lesions affecting the retina, RPE and choroid. A wide range of inflammatory and infectious conditions may also cause white spots. Areas of retinitis are characterised by a cloudy yellow-white appearance with indistinct edges (Figure 1). Choroiditis is deeper, with yellow or greyish patches that are more clearly demarcated (Figure 2). Retinal blood vessels lie over the lesions and inactive lesions form areas of well-defined chorioretinal atrophy.

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