In Focus: Genetics study identifies changes linked to foveal defects

Researchers at the University of Leicester have explored how genetic defects influenced vision development and created problems in developing babies’ eyes.

The international study involved 20 centres and was the largest of its kind to date to examine the genes associated with arrested development of the fovea.

Over 900 cases from around the world were examined in the study, which was published in the Ophthalmology journal. Researchers were able to identify the spectrum of genetic changes behind these foveal defects and at which point they occur in the development of the unborn baby.

Researchers explained that arrested development of the fovea, or foveal hypoplasia, was rare, and was often caused by genetic changes. They said the lifelong condition could have serious consequences and could affect the child’s ability to read, drive and complete other daily tasks.