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Measuring macular pigment

Clinical Practice
Professors John M Nolan and Stephen Beatty give their personal view of technology for measuring macular pigment levels

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We are writing this article for eye care specialists, as we believe it is incumbent upon us as researchers who have studied and measured MP for over 12 years to present our informed opinion regarding the measurement of MP in living subjects. We believe this article is necessary in response to two recent articles published in Optician claiming macular screening in 90 seconds: 'The new MPS II - Macular screening in 90 secs!' (Optician 21.12.12) and 'Instrument supplier plans AMD campaign' (Optician 30.11.12).

Scientists have been debating the various approaches to MP measurement for over 20 years.4-6 Firstly, it is important to point out that it is extremely difficult to measure MP. Remember; when we attempt to measure MP, we are attempting to measure nutrients located at the macula, and therefore we must take into account all the optical variables (eg lens, cornea, vitreous, etc) that may influence or confound the values yielded with any given instrument. Therefore, the key issue for any method is a firm understanding of the assumptions upon which it is premised, and how these may relate to the optical properties of the human eye and the visual system. Add to this that, just like people, every eye is different. In other words, no method is perfect or without its limitations.

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