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Pseudoexfoliation glaucoma (PXF)

Disease
Exfoliation glaucoma, Pseudoexfoliation syndrome (PEX), Exfoliation syndrome (XFS)

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Pseudoexfoliation (PXF) glaucoma is a secondary open-angle glaucoma, arising from trabecular blockage. Pseudoexfoliation (or exfoliation) refers to a grey-white flaky material observed on the anterior surface of the crystalline lens.

The material appears as if there has been shedding of epithelial cells from the lens capsule, hence the name 'exfoliation'. However, the material is believed to be similar to amyloid and appears to be systemically synthesised, as well as from lens capsule, iris and ciliary body.

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