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These criteria exclude a range of diseases including intracranial space-occupying lesions, hydrocephalus and various inflammatory and infective processes. The raised ICP in pseudotumour cerebri has therefore been described as 'idiopathic'. However, it has a tendency to affect obese women in the child-bearing years, suggesting that abnormal hormonal activity may contribute to the syndrome. Several medications have also been implicated, including tetracycline, nalidixic acid, oral contraceptives, lithium, corticosteroids and amiodarone.
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