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A multi-centre study published in July's Eye & Contact Lens 1 investigated inflammatory and mechanical complications associated with up to 30 nights' continuous wear of lotrafilcon A lenses. A total of 317 subjects (286 current wearers and 31 new wearers) were followed for three years.
The authors conclude that the rate of adverse events with lotrafilcon A was low in this cohort, with one-third of inflammatory events occurring in the first three months of wear. The rate of these events may be lower in practice than previously reported, they say. In this study, no subjects experienced microbial keratitis (MK), the most serious complication of CL wear.
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