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While the goal of eliminating hypoxia has largely been resolved with the advent of silicone hydrogel materials, the equally important criteria for patient acceptance - comfort - has yet to be completely solved. Discontinuation from contact lens wear occurs as a result of poor comfort in 72 per cent of the cases,2 with dryness being the most commonly reported symptom.3-5 Symptoms of discomfort and dryness with contact lens wear have been related to lens movement and edge profiles,6 dehydratation,7 protein and lipid deposition,8 modulus of rigidity, wettability and lubricity,9,10 and solution toxicity.11,12
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