Retinal pigment epithelium (RPE) detachment appears to result from disorders that disrupt the normal junction between the basement membrane of the RPE and the inner collagenous Bruch's membrane. This disruption may be associated with:
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Associated conditions
The most common condition associated with RPE detachment is age-related macular degeneration. Other possible associated ocular conditions are listed below. Uncomplicated idiopathic serous detachments of the RPE often resolve spontaneously, however, haemorrhage, CNV, and disciform scarring may affect those detachments associated with other choroidal pathology.
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