AMD associated cells discovered

Researchers utilising a new single-cell genome sequencing technique have identified the specific types of cells in the retina associated with blindness in old age.

A study published in Nature Communications shows that three different cell types contribute to degeneration of the macula: glial cells that support and insulate nerves, vascular cells which provide blood to the retina and cone cells that help the retina detect light.

Age related macular degeneration is one of the leading causes of blindness in the elderly, and only a limited number of effective long-term treatment options are currently available.

‘This study helps pinpoint cell types that can be investigated closely to develop new types of therapeutics,’ explained Brian Hafler from Yale University, the study’s co-senior author.