Low concentration drops effective against myopia

A randomised clinical trial has found nightly use of 0.05% atropine eyedrops resulted in a significantly lower incidence of myopia and lower percentage of participants with a fast myopic shift after two years compared with placebo.

The Chinese University of Hong Kong Eye Centre enrolled 474 non-myopic children aged four to nine years with cycloplegic spherical equivalent between +1.00D to 0.00D and astigmatism less than -1.00D.

Nightly use of 0.05% atropine, 0.01% atropine, and placebo eyedrops resulted in a two-year cumulative incidence of myopia of 28.4%, 45.9%, and 53.0%, respectively.