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NASA discovery may aid cataract detection

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A laser device developed by NASA senior scientist Dr Manuel Datiles to study crystals in space is also able to detect levels of the protein alpha-crystillin in the human lens.

A laser device developed by NASA senior scientist Dr Manuel Datiles to study crystals in space is also able to detect levels of the protein alpha-crystillin in the human lens.

Recent studies have shown that a reduction in alpha-crystallin levels in the crystalline lens is an early indicator of cataract progression.  The protein has a protective role in 'mopping up' other protein denatured by factors such as cigarette smoke and ultraviolet light exposure. Once levels are depleted the lens tends to opacify. It is hoped the new device may not only help predict the potential for cataract in patients but also help researchers measure the effects of potentially beneficial interventions aimed at preventing cataract.

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