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New hope for AMD therapy

Clinical

Donation of drusen material from an eye with age-related macular degeneration (AMD) may stimulate the production of chemicals that protect against the wet form of the disease.

A study from Trinity College Dublin has shown how drusen from donor eyes with AMD can trigger increased production of two chemicals, which are thought to have an anti-angiogenic role.

Dr Matthew Campbell said: 'Our results directly suggest that controlling or indeed augmenting the levels of IL-18 in the retinas of patients with dry AMD could prevent the development of the wet form of the disease, which leads us to an exciting new prospect for a novel therapy for AMD.'

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