Supplements

Myopia Guide: Day and Night CLs

Events
The latest data on the efficacy of the Menicon Bloom Myopia Control Management System

The Menicon Bloom Myopia Control Management System was introduced a few years back, and is unique in its use of a combination of rigid corneal and soft contact lenses. The system features two components: Menicon Bloom Day, an extended depth of focus daily disposable soft contact lens (made of etafilcon A) with CE-approval specifically for myopia progression control (figure 1); and Menicon Bloom Night, the first CE-approved orthokeratology rigid corneal contact lens for myopia control management in Europe (figure 2). The lens is made of the hyperpermeable Menicon Z material.


Efficacy

Initial data supported the efficacy, safety and acceptance of Menicon Bloom Day and Menicon Bloom Night as successful treatment options for myopia control. One retrospective case series analysis, from 10 practice locations in the US, analysed data from 32 patients (ages six to 19 years), and showed Menicon Bloom Day to significantly slow myopia progression in children1. A follow-up retrospective analysis involving 15 practice locations in the US, which analysed data from 192 patients who wore Menicon Bloom Day lenses for about six years, further supported the efficacy of this unique myopia control lens in slowing myopia progression (Menicon Data on File, 2021).

Other studies have shown how the extended depth of focus design corrects peripheral hyperopia, the putative stimulus responsible for myopia progression 2, 3.

Meanwhile, several peer-reviewed studies conducted with Menicon Bloom Night for myopia control treatment confirmed significant levels of efficacy4-6. More recent results have demonstrated how Menicon Bloom Night can reduce myopia progression in children over long periods of contact lens wear7.


Safety

Like any other treatment, contact lens wear can be associated with the development of adverse events and complications. However, recent large studies, including systematic reviews and meta-analyses, have demonstrated Menicon Bloom Day and Menicon Bloom Night type contact lenses are safe to use in paediatric pupulations8 if fitted correctly by an eye care professional according to the manufacturer’s instructions.

A review of nine prospective studies, conducted in children aged from seven to 19 years and wearing soft contact lenses (representing 1,800 patient years of wear) reported the incidence of corneal infiltrative events in children was no higher than that found in adults.

The incidence was found to be markedly lower in the youngest age range of eight to 11 years in comparison with adults9. A more recent data analysis from six randomised myopia control trials conducted with daily disposable hydrogel (etafilcon A) contact lenses in 663 myopic children (aged seven to 15 years at baseline) reported no significant or serious ocular adverse events, including corneal infections or serious corneal infiltrative events, indicating daily disposable (etafilcon A) hydrogel contact lenses are safe for use in children10. All together, these results support the safety of Menicon Bloom Day daily disposable soft contact lenses for the purposes of myopia progression control in children.


Conclusion

Though published data for long-term efficacy is thin on the ground, what has been published seems to suggest that the Menicon Bloom Myopia Control Management System is both safe and effective. I look forward to more being published in the near future.


References

  1. Cooper J et al. Case series analysis of myopic progression control with a unique extended depth of focus multifocal contact lens. Eye & Contact Lens, 2018;44(5):e16-e24
  2. Payor R et al. Feasibility testing of a novel soft contact lens optical design to reduce suspected risk factors for the progression of juvenile onset myopia. Investigative Ophthalmology and Visual Science, 2014;55:E-abstract 3638
  3. Dillehay S et al. Comparison of three power levels of a novel soft contact lens optical design to reduce suspected risk factors for the progression of juvenile onset myopia. Investigative Ophthalmology and Visual Science, 2014;55:E-abstract 3637
  4. Cho P, Cheung SW. Retardation of myopia in orthokeratology (ROMIO) study: a 2-year randomized clinical trial. Investigative Ophthalmology and Visual Science, 2012;53(11):7077-85
  5. Santodomingo-Rubido J et al. Myopia control with orthokeratology contact lenses in Spain: Refractive and biometric changes. Investigative Ophthalmology and Visual Science, 2012;53(8):5060-5
  6. Chen C et al. Myopia control using toric orthokeratology (TO-SEE study). Investigative Ophthalmology and Visual Science, 2013;54(10):6510-7
  7. Santodomingo-Rubido J et al. Long-term efficacy of orthokeratology contact lens wear in controlling the progression of childhood myopia. Current Eye Research, 2017;42(5):713-20
  8. Cheng X et al. Safety of soft contact lenses in children: Retrospective review of six randomized controlled trials of myopia control. Acta Ophthalmologica, 2020;98(3):e346-e351
  9. Bullimore MA. The Safety of Soft Contact Lenses in Children. Optometry and Vision Science, 2017;94(6):638-46
  10. Brennan NA et al. Safety of contact lenses in pediatrics: data analysis from six randomized myopia control trials. Optometry and Vision Science, 2019;96:E-abstract: 195208