Managing with glasses

Much of the current interest in myopia management has been around contact lens interventions, either via orthokeratology with rigid lenses or using simultaneous vision multifocal or specific-design dual focus soft contact lenses. In each case, the production of a hyperopic shell (or myopic defocus) in front of the retina is seen to result in the slowing of axial length increase. It seems the defocus influences the MYP1 locus, associated with splicing-defective cone opsin genes (OPN1LW and OPN1MW), and this has led to the hypothesis that contrast signalling in the retina may play an important role in the development and progression of myopia.