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Drops could prevent optic nerve damage

Italian researchers claim that eye drops containing nerve growth factor may be able to protect the optic nerve and retinal nerve cells from the damage caused by glaucoma and in some cases even restore some vision.

Italian researchers claim that eye drops containing nerve growth factor may be able to protect the optic nerve and retinal nerve cells from the damage caused by glaucoma and in some cases even restore some vision.

The team led by Dr Stefano Bonini, professor and chairman of the department of ophthalmology at the University of Rome Campus Bio-Medico, found that the topical use of nerve growth factor, which is easily absorbed by the eye in drop form, spared retinal ganglion cells (RGCs) from nerve damage caused by the build-up of eye pressure associated with glaucoma.

The team tested the effect of RGCs in rats whose eyes had been injected with saline to induce the effect of glaucoma. Those given the eye drops showed decreased levels of RGC loss. The untreated rats lost 40 per cent of their RGCs through cell death resulting from seven weeks of raised IOP.

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