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Indocyanine green angiography: clinical uses in AMD

Clinical Practice
Uliana Gout, Dr Irina Gout and Sundeep Kheterpal look at the usefulness of indocyanine green angiography in the monitoring of AMD

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Indocyanine green (ICG), a synthetic fluorescent dye, has historically been used in the photographic industry, and was first applied in medical imaging in 1956.

ICG is manufactured in a green, blue-green or green-black powder form, containing a small amount of sodium iodide. This dye has fluorescent qualities. ICG's peak absorption is between 800-810nm, with an emission peak of 835nm (within the infrared spectrum),6 while fluorescein sodium's peak absorption is 485-500nm, and its peak emission is 520-530nm7 (Figure 1).

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